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Abnova
SH3PXD2A Polyclonal Antibody, MaxPab™
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Product Details
H00009644-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SH3PXD2A (AAI56573.1, 1 a.a. approximately 1105 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLAYCVQDAT VVDVEKRRNP SKHYVYIINV TWSDSTSQTI YRRYSKFFDL QMQLLDKFPI EGGQKDPKQR IIPFLPGKIL FRRSHIRDVA VKRLKPIDEY CRALVRLPPH ISQCDEVFRF FEARPEDVNP PKEDYGSSKR KSVWLSSWAE SPKKDVTGAD ATAEPMILEQ YVVVSNYKKQ ENSELSLQAG EVVDVIEKNE SGWWFVSTSE EQGWVPATYL EAQNGTRDDS DINTSKTGEE EKYVTVQPYT SQSKDEIGFE KGVTVEVIRK NLEGWWYIRY LGKEGWAPAS YLKKAKDDLP TRKKNLAGPV EIIGNIMEIS NLLNKKASGD KETPPAEGEG HEAPIAKKEI SLPILCNASN GSAVGVPDRT VSRLAQGSPA VARIAPQRAQ ISSPNLRTRP PPRRESSLGF QLPKPPEPPS VEVEYYTIAE FQSCISDGIS FRGGQKAEVI DKNSGGWWYV QIGEKEGWAP ASYIDKRKKP NLSRRTSTLT RPKVPPPAPP SKPKEAEEGP TGASESQDSP RKLKYEEPEY DIPAFGFDSE PELSEEPVED RASGERRPAQ PHRPSPASSL QRARFKVGES SEDVALEEET IYENEGFRPY AEDTLSARGS SGDSDSPGSS SLSLTRKNSP KSGSPKSSSL LKLKAEKNAQ AEMGKNHSSA SFSSSITINT TCCSSSSSSS SSLSKTSGDL KPRSASDAGI RGTPKVRAKK DADANAGLTS CPRAKPSVRP KPFLNRAESQ SQEKMDISTL RRQLRPTGQL RGGLKGSKSE DSELPPQTAS EAPSEGSRRS SSDLITLPAT TPPCPTKKEW EGPATSYMTC SAYQKVQDSE ISFPAGVEVQ VLEKQESGWW YVRFGELEGW APSHYLVLDE NEQPDPSGKE LDTVPAKGRQ NEGKSDSLEK IERRVQALNT VNQSKKATPP IPSKPPGGFG KTSGTPAVKM RNGVRQVAVR PQSVFVSPPP KDNNLSCALR RNESLTATDG LRGVRRNSSF STARSAAAEA KGRLAERAAS QGSDSPLLPA QRNSIPVSPV RPKPIEKSQF IHNNLKDVYV SIADYEGDEE TAGFQEGVSM EVLERNPNGW WYCQILDGVK PFKGWVPSNY LEKKN
Target Information
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adapter protein TKS5; adaptor protein TKS5; Five SH3 domain-containing protein; SH3 and PX domain-containing protein 2A; SH3 multiple domains 1; SH3 multiple domains protein 1; Tyrosine kinase substrate with five SH3 domains
Gene Aliases: FISH; KIAA0418; SH3MD1; SH3PXD2A; TKS5
UniProt ID: (Human) Q5TCZ1
Entrez Gene ID: (Human) 9644
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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