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Invitrogen
SGEF Polyclonal Antibody
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Product Details
PA5-65547
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human SGEF
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2664366
Product Specific Information
Immunogen sequence: ESEVDNDVDSP GSLRRGLRST SYRRAVVSGF DFDSPTSSKK KNRMSQPVLK VVMEDKEKFS SLGRIKKKML KGQGTFDGEE NAVLYQNYKE KALDIDSDEE SEPKEQKSDE KIVIHHKPLR STWSQLSAVK RKGLSQ
Highest antigen sequence identity to the following orthologs - mouse 93%, rat 95%.
Target Information
Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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