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PA5-19780 targets Protein C inhibitor in WB applications and shows reactivity with Human samples.
The PA5-19780 immunogen is synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Human Protein C inhibitor.
PA5-19780 detects Protein C inhibitor which has a predicted molecular weight of approximately 54 kDa.
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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