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Invitrogen
SERCA3 ATPase Polyclonal Antibody
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FIGURE: 1 / 2
SERCA3 ATPase Antibody (PA1-910A) in IHC
Molecular vision 2007 -
Figure 6 Molecular markers of endoplasmic reticulum (ER) reveal distinct retinal distribution and lamination patterns. A - D : Confocal image of retina triple labeled for calreticulin, COX IV and PNA. Scale bar equal 20 mum. A : Retina stained for calreticulin, a Ca 2+ -binding protein present in all ER lumen. Note the intense labeling in the IS, OPL and INL. B : Location of calreticulin (red) and COX ... View More
Product Details
PA1-910A
Applications
Tested Dilution
Publications
Product Specifications
Published species
Dog,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic Peptide: V(29) T D A R E R Y G P N(39).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2061458
Product Specific Information
PA1-910A detects sarcoplasmic or endoplasmic reticulum calcium ATPase 3 (SERCA3) mouse and rat samples. This antibody does not detect other SERCA isoforms.
PA1-910A has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~97 kDa protein representing recombinant SERCA3 from rat samples.
PA1-910A immunizing peptide corresponds to amino acid residues 29-39 from rat and mouse SERCA3. PA1-910A immunizing peptide (Cat. # PEP-015) is available for neutralization and control experiments.
Target Information
ATP dependent calcium pumps are responsible in part for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium ATPases (SERCA). The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific isoform expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types. SERCA3 has been found to co-express with SERCA2b in platelets, mast cells, lymphoid cells, and epithelial cells. Due to this pattern of expression it is referred to as the non-muscle form of SERCA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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