Invitrogen

SERCA2 ATPase Polyclonal Antibody

SERCA2 ATPase Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 4

SERCA2 ATPase Antibody (PA5-29380) in IHC (P)

Immunohistochemical analysis of SERCA2 in the cytosol of paraffin-embedded rat brain stem tissue using a SERCA2 polyclonal antibody (Product # PA5-29380) at a dilution of 1:500.

SERCA2 ATPase Antibody in Western Blot (WB)

Product Image Gallery

Product Details

PA5-29380

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:1,000

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fragment corresponding to a region within amino acids 237 and 538 of Human SERCA2

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

AB_2546856

Product Specific Information

PA5-29380 targets SERCA2 in IHC (P) and WB applications and shows reactivity with Human samples.

The PA5-29380 immunogen is recombinant fragment corresponding to a region within amino acids 237 and 538 of Human SERCA2.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Target Information

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?

Let us know so we can reference it here.

Cite this product

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more