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Invitrogen
SBF1 Polyclonal Antibody
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Product Details
PA5-66780
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human SBF1
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2662275
Product Specific Information
Immunogen sequence: LRSCTFQLLKM AFDEEVGSDS AELFRKQLHK LRYPPDIRAT FAFTLGSAHT PGRPPRVTKD KGPSLRTLSR NLVKNAKKTI GRQHVTRKKY N
Highest antigen sequence identity to the following orthologs - mouse 97%, rat 97%.
Target Information
Probable pseudophosphatase. Lacks several amino acids in the catalytic pocket which renders it catalytically inactive as a phosphatase. The pocket is however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts. According to PubMed:20937701, may function as a guanine nucleotide exchange factor (GEF) activating RAB28. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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