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Invitrogen
RYK Polyclonal Antibody
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Product Details
PA1-30713
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide conjugated to KLH, corresponding to amino acids 576-592 of Human RYK.
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_1960556
Product Specific Information
PA1-30713 detects RYK from human samples.
PA1-30713 has been successfully used in immunohistochemistry (frozen tissue), immunohistochemistry (paraffin tissue), and Western blot applications. A suggested positive control for this product is Jurkat cell lysate.
The PA1-30713 immunogen is Synthetic peptide conjugated to KLH, corresponding to amino acids 576-592 of Human RYK.
Target Information
RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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