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Invitrogen
RFC5 Polyclonal Antibody
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Product Details
PA1-26571
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a portion of human Replication Factor C 5 36 kDa subunit encoded within exon 1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Storage conditions
4°C, do not freeze
Shipping conditions
Wet ice
RRID
AB_2178604
Product Specific Information
PA1-26571 detects RFC5 from human samples. PA1-26571 will not react with mouse or rat.
PA1-26571 has been successfully used in Western blot procedures where a band of 36 kDa is predicted to be detected. HeLa cell nucleaer extract is recommended as a positive control fo PA1-26571.
The PA1-26571 immunogen is a synthetic peptide corresponding to a portion of human Replication Factor C 5 36 kDa subunit encoded within exon 1.
Target Information
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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