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PA1-26567 detects RFC2 from human samples. PA1-26567 will not react with mouse.
PA1-26567 has been successfully used in Western blot procedures.
The PA1-26567 immunogen is a synthetic peptide corresponding to a portion of human Replication Factor C 2 40 kDa subunit encoded within exon 1.
This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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