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Human Rad1 is a homolog of Schizosaccharomyces pombe Rad1.
Suggested positive control: Hela whole cell lysate, 293 whole cell lysate, 293, HeLa, or NIH-3T3, 3T3 whole cell lysate.
Rad1 is a component of a heterotrimeric PCNA-like complex that contains Rad9 and Hus1 proteins. This complex is involved in the 9-1-1 cell cycle checkpoing response complex that plays a major role in DNA repair, by associating with Rad17 and several components of the PCNA-loading heteropentamer replication factor C. Mutants has been shown to partially restore radiation resistance and G2-checkpoint activity. It has also been shown to possess exonuclease activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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