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Invitrogen
RAB6A Polyclonal Antibody
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Product Details
PA5-95528
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence of human RAB6A (RRVAAALPGMESTQDRSREDMIDIKLEKPQEQPVSE).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2807330
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human MDA-MB-453 whole cell, human SK-OV-3 whole cell, Human A431 whole cell, rat testis tissue, mouse brain tissue, mouse HEPA1-6 whole cell. IHC: human placenta tissue, rat small intestine tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
Rab proteins are also an integral part of endocytic pathways. Rab 6A is a ubiquitously expressed member of the Rab family of proteins and localizes to the Golgi membrane where it regulates retrograde transport from the late endosomes via the Golgi to endoplasmic reticulum (ER) pathway. Three isoforms exist due to alternative splicing events, namely the ubiquitously expressed isoforms Rab 6A' and Rab 6A, and the brain-specific isoform Rab 6B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Rab GTPase; Rab-6; RAB6, member RAS oncogene family; RAB6B, member RAS oncogene family; Ras-related protein Rab-6A
Gene Aliases: 2610028L11Rik; AA419671; MNCb-1660; RAB6; RAB6A; Rab6b; RCO4-3
UniProt ID: (Human) P20340, (Rat) Q9WVB1, (Mouse) P35279
Entrez Gene ID: (Human) 5870, (Rat) 84379, (Mouse) 19346
protein targeting to Golgi
retrograde vesicle-mediated transport, Golgi to ER
small GTPase mediated signal transduction
viral process
peptidyl-cysteine methylation
antigen processing and presentation
protein localization to Golgi apparatus
early endosome to Golgi transport
minus-end-directed organelle transport along microtubule
intracellular protein transport
intra-Golgi vesicle-mediated transport
metabolic process
Rab protein signal transduction
positive regulation of ATPase activity
retrograde transport, endosome to Golgi
Golgi vesicle transport
transport
protein transport
vesicle-mediated transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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