Product References
Mutational and functional analysis of the tumor-suppressor PTPRD in human melanoma.
Human mutation
Walia V,Prickett TD,Kim JS,Gartner JJ,Lin JC,Zhou M,Rosenberg SA,Elble RC,Solomon DA,Waldman T,Samuels Y
03-7700 was used in western blot to investigate protein tyrosine phosphatases in cases of cutaneous metastatic melanoma
Sat Nov 01 00:00:00 UTC 2014
Heat shock protein 90 has roles in intracellular calcium homeostasis, protein tyrosine phosphorylation regulation, and progesterone-responsive sperm function in human sperm.
PloS one
Li K,Xue Y,Chen A,Jiang Y,Xie H,Shi Q,Zhang S,Ni Y
03-7700 was used in western blot to examine the mechanism by which heat shock protein 90 affects human sperm function
Mon Nov 23 00:00:00 UTC 2015
Human red blood cells alterations in primary aldosteronism.
The Journal of clinical endocrinology and metabolism
Bordin L,Donà G,Sabbadin C,Ragazzi E,Andrisani A,Ambrosini G,Brunati AM,Clari G,Armanini D
03-7700 was used in western blot to use the diamide-induced Tyr phosphorylation level of membrane band 3 to monitor the redox status of red blood cells
Sat Jun 01 00:00:00 UTC 2013
KIR3DL2 binds to HLA-B27 dimers and free H chains more strongly than other HLA class I and promotes the expansion of T cells in ankylosing spondylitis.
Journal of immunology (Baltimore, Md. : 1950)
Wong-Baeza I,Ridley A,Shaw J,Hatano H,Rysnik O,McHugh K,Piper C,Brackenbridge S,Fernandes R,Chan A,Bowness P,Kollnberger S
03-7799 was used in western blot to study KIR3DL2-expressing leukocytes observed in B27(+) spondyloarthritis.
Mon Apr 01 00:00:00 UTC 2013
Long-term exposure of gastrointestinal stromal tumor cells to sunitinib induces epigenetic silencing of the PTEN gene.
International journal of cancer
Yang J,Ikezoe T,Nishioka C,Takezaki Y,Hanazaki K,Taguchi T,Yokoyama A
03-7700 was used in immunoprecipitation to elucidate the mechanism of sunitinib resistance
Wed Feb 15 00:00:00 UTC 2012
Long-term exposure of gastrointestinal stromal tumor cells to sunitinib induces epigenetic silencing of the PTEN gene.
International journal of cancer
Yang J,Ikezoe T,Nishioka C,Takezaki Y,Hanazaki K,Taguchi T,Yokoyama A
03-7700 was used in immunoprecipitation to elucidate the mechanism of sunitinib resistance
Wed Feb 15 00:00:00 UTC 2012
Effect of cellular senescence on the albumin permeability of blood-derived endothelial cells.
American journal of physiology. Heart and circulatory physiology
Cheung TM,Ganatra MP,Peters EB,Truskey GA
03-7700 was used in western blot to study permeability and tight junctions in endothelial cells derived from human cord blood
Sat Dec 01 00:00:00 UTC 2012
Heparin promotes platelet responsiveness by potentiating αIIbβ3-mediated outside-in signaling.
Blood
Gao C,Boylan B,Fang J,Wilcox DA,Newman DK,Newman PJ
03-7700 was used in western blot to investigate the mechanism by which unfractionated heparin activates platelets
Thu May 05 00:00:00 UTC 2011
Hormone signaling linked to silkmoth sex pheromone biosynthesis involves Ca2+/calmodulin-dependent protein kinase II-mediated phosphorylation of the insect PAT family protein Bombyx mori lipid storage droplet protein-1 (BmLsd1).
The Journal of biological chemistry
Ohnishi A,Hull JJ,Kaji M,Hashimoto K,Lee JM,Tsuneizumi K,Suzuki T,Dohmae N,Matsumoto S
03-7700 was used in western blot to investigate molecular components that regulate triacylglycerol lipolysis in pheromone gland cells
Fri Jul 08 00:00:00 UTC 2011
PECAM-1 functions as a negative regulator of laminin-induced platelet activation.
Journal of thrombosis and haemostasis : JTH
Crockett J,Newman DK,Newman PJ
03-7700 was used in western blot to examine the effects of subendothelial matrix components on platelets
Thu Jul 01 00:00:00 UTC 2010
Extended kinase profile and properties of the protein kinase inhibitor nilotinib.
Biochimica et biophysica acta
Manley PW,Drueckes P,Fendrich G,Furet P,Liebetanz J,Martiny-Baron G,Mestan J,Trappe J,Wartmann M,Fabbro D
03-7700 was used in ELISA to discuss the use of nilotinib as a protein kinase inhibitor
Mon Mar 01 00:00:00 UTC 2010
Characterization of in vivo keratin 19 phosphorylation on tyrosine-391.
PloS one
Zhou Q,Snider NT,Liao J,Li DH,Hong A,Ku NO,Cartwright CA,Omary MB
03-7700 was used in western blot to examine phosphorylation of keratin polypeptide 19
Mon Oct 25 00:00:00 UTC 2010
An acidic extracellular pH induces Src kinase-dependent loss of beta-catenin from the adherens junction.
Cancer letters
Chen KH,Tung PY,Wu JC,Chen Y,Chen PC,Huang SH,Wang SM
03-7799 was used in western blot to investigate the effect of an acidic microenvironment on the migration and invasive of cancer cells
Mon Aug 18 00:00:00 UTC 2008
Synergistic antitumor effect of S-1 and the epidermal growth factor receptor inhibitor gefitinib in non-small cell lung cancer cell lines: role of gefitinib-induced down-regulation of thymidylate synthase.
Molecular cancer therapeutics
Okabe T,Okamoto I,Tsukioka S,Uchida J,Iwasa T,Yoshida T,Hatashita E,Yamada Y,Satoh T,Tamura K,Fukuoka M,Nakagawa K
03-7700 was used in western blot to determine the antiproliferative effect of the combination of fluorouracil S-1 and gefitinib in non-small cell lung cancer cells of differing epidermal growth factor receptor status
Sat Mar 01 00:00:00 UTC 2008
Mechanism of activation and inhibition of the HER4/ErbB4 kinase.
Structure (London, England : 1993)
Qiu C,Tarrant MK,Choi SH,Sathyamurthy A,Bose R,Banjade S,Pal A,Bornmann WG,Lemmon MA,Cole PA,Leahy DJ
03-7700 was used in western blot to show the crystal structures of the ErbB4 kinase domain in active and lapatinib-inhibited forms
Sat Mar 01 00:00:00 UTC 2008
Human cytomegalovirus immediate-early-gene expression disrupts embryogenesis in transgenic Drosophila.
Transgenic research
Steinberg R,Shemer-Avni Y,Adler N,Neuman-Silberberg S
03-7700 was used in immunohistochemistry to develop and use a transgenic Drosophila model system to examine the effects of viral infection on embryonic development
Fri Feb 01 00:00:00 UTC 2008
Cortical development in the presenilin-1 null mutant mouse fails after splitting of the preplate and is not due to a failure of reelin-dependent signaling.
Developmental dynamics : an official publication of the American Association of Anatomists
De Gasperi R,Gama Sosa MA,Wen PH,Li J,Perez GM,Curran T,Elder GA
03-7799 was used in western blot to test if reelin signaling is disrupted in Psen1 knockout mice
Mon Sep 01 00:00:00 UTC 2008
The epidermal growth factor receptor (EGFR) is proteolytically modified by the Matriptase-Prostasin serine protease cascade in cultured epithelial cells.
Biochimica et biophysica acta
Chen M,Chen LM,Lin CY,Chai KX
Thu May 01 00:00:00 UTC 2008
EGF-independent activation of cell-surface EGF receptors harboring mutations found in gefitinib-sensitive lung cancer.
Oncogene
Choi SH,Mendrola JM,Lemmon MA
37700 was used in western blot to study EGF-independent activation of mutant cell-surface EGF receptors in gefitinib-sensitive lung cancer
Thu Mar 08 00:00:00 UTC 2007
The IREM-1 (CD300f) inhibitory receptor associates with the p85alpha subunit of phosphoinositide 3-kinase.
Journal of immunology (Baltimore, Md. : 1950)
Alvarez-Errico D,Sayós J,López-Botet M
03-7799 was used in western blot to study the interactions of IREM-1 myeloid cell receptor with other proteins to assess its function
Mon Jan 15 00:00:00 UTC 2007
Cell-specific effects of insulin receptor substrate-1 deficiency on normal and IGF-I-mediated colon growth.
American journal of physiology. Gastrointestinal and liver physiology
Simmons JG,Ling Y,Wilkins H,Fuller CR,D'Ercole AJ,Fagin J,Lund PK
37700 was used in western blot to test if there is cell type-specific dependence on insulin receptor substrate-1 as a mediator of insulin-like growth factor I action
Thu Nov 01 00:00:00 UTC 2007
Activation of extracellular signal-regulated kinase by 12-hydroxyheptadecatrienoic acid in prostate cancer PC3 cells.
Archives of biochemistry and biophysics
Li X,Wei J,Tai HH
37700 was used in western blot to study the mechanism by which 12-hydroxyheptadecatrienoic acid activates ERK in prostate cancer cells
Thu Nov 01 00:00:00 UTC 2007
An efficient method for protein phosphorylation using the artificially introduced of cognate-binding modules into kinases and substrates.
Journal of biotechnology
Kobashigawa Y,Naito M,Inagaki F
03-7799 was used in western blot to utilize a protein phosphorylation method via artificially introducing cognate-binding modules into substrates and enzymes
Sun Sep 30 00:00:00 UTC 2007
Generation of intracellular domain of insulin receptor tyrosine kinase by gamma-secretase.
Biochemical and biophysical research communications
Kasuga K,Kaneko H,Nishizawa M,Onodera O,Ikeuchi T
03-7799 was used in immunoprecipitation to test if the insulin receptor undergoes presenilin/gamma-secretase-dependent processing
Fri Aug 17 00:00:00 UTC 2007
Quantitative comparison of IMAC and TiO2 surfaces used in the study of regulated, dynamic protein phosphorylation.
Journal of the American Society for Mass Spectrometry
Liang X,Fonnum G,Hajivandi M,Stene T,Kjus NH,Ragnhildstveit E,Amshey JW,Predki P,Pope RM
03-7799 was used in immunoprecipitation to design a technique utilizing isotope tagging reagents for relative and absolute quantification labeling to compare commercial and prototypal immobilized metal affinity chelate (IMAC) and metal oxide resins
Thu Nov 01 00:00:00 UTC 2007
Monoclonal antibody cetuximab binds to and down-regulates constitutively activated epidermal growth factor receptor vIII on the cell surface.
Anticancer research
Patel D,Lahiji A,Patel S,Franklin M,Jimenez X,Hicklin DJ,Kang X
03-7799 was used in western blot to determine the effect of cetuximab monoclonal antibody on constitutively activated epidermal growth factor receptor vIII on the cell surface
Tue Nov 27 00:00:00 UTC 2007
Endogenous phosphotyrosine signaling in zebrafish embryos.
Molecular & cellular proteomics : MCP
Lemeer S,Ruijtenbeek R,Pinkse MW,Jopling C,Heck AJ,den Hertog J,Slijper M
03-7799 was used in western blot to evaluate endogenous phosphotyrosine signaling in developing zebrafish embryos
Sat Dec 01 00:00:00 UTC 2007
Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration.
Blood
Favier B,Alam A,Barron P,Bonnin J,Laboudie P,Fons P,Mandron M,Herault JP,Neufeld G,Savi P,Herbert JM,Bono F
03-7700 was used in western blot to suggest that NRP2 acts as a coreceptor that enhances human endothelial cell responses induced by VEGF-A and VEGF-C
Tue Aug 15 00:00:00 UTC 2006
Preclinical antitumor activity of BMS-599626, a pan-HER kinase inhibitor that inhibits HER1/HER2 homodimer and heterodimer signaling.
Clinical cancer research : an official journal of the American Association for Cancer Research
Wong TW,Lee FY,Yu C,Luo FR,Oppenheimer S,Zhang H,Smykla RA,Mastalerz H,Fink BE,Hunt JT,Gavai AV,Vite GD
03-7799 was used in western blot to assess the ability of BMS-599626 to modulate human epidermal growth factor receptor 1 and 2
Sun Oct 15 00:00:00 UTC 2006
Macrophage activation increases the invasive properties of hepatoma cells by destabilization of the adherens junction.
FEBS letters
Lin CY,Lin CJ,Chen KH,Wu JC,Huang SH,Wang SM
03-7799 was used in western blot to elucidate the cellular mechanisms by which activated macrophages contribute to tumor progression
Mon May 29 00:00:00 UTC 2006
Photoreceptor morphogenesis in the Drosophila compound eye: R1-R6 rhabdomeres become twisted just before eclosion.
The Journal of comparative neurology
Baumann O,Lutz K
03-7700 was used in immunohistochemistry to study rhabdomere twisting
Fri Sep 01 00:00:00 UTC 2006
Binding of sialyl Lewis X antigen to lectin-like receptors on NK cells induces cytotoxicity and tyrosine phosphorylation of a 17-kDa protein.
Biochimica et biophysica acta
Higai K,Ichikawa A,Matsumoto K
03-7799 was used in western blot to identify compounds that bind the lectin-like receptors on human natural killer-derived KHYG cells
Fri Sep 01 00:00:00 UTC 2006
Identification of signaling molecules mediating corticotropin-releasing hormone-R1alpha-mitogen-activated protein kinase (MAPK) interactions: the critical role of phosphatidylinositol 3-kinase in regulating ERK1/2 but not p38 MAPK activation.
Molecular endocrinology (Baltimore, Md.)
Punn A,Levine MA,Grammatopoulos DK
03-7700 was used in western blot to investigate signaling mechanisms and molecules involved in CRH-receptor 1-mediated ERK1/2 and p38 MAPK activation
Fri Dec 01 00:00:00 UTC 2006
Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research
Ishibe T,Nakayama T,Okamoto T,Aoyama T,Nishijo K,Shibata KR,Shima Y,Nagayama S,Katagiri T,Nakamura Y,Nakamura T,Toguchida J
03-7799 was used in western blot to assess the involvement of fibroblast growth factor signals in synovial sarcoma
Fri Apr 01 00:00:00 UTC 2005
A mixture of environmental contaminants increases cAMP-dependent protein kinase in Spisula embryos.
Environmental toxicology and pharmacology
Kreiling JA,Stephens RE,Reinisch CL
03-7700 was used in western blot to characterize surf clam embryos exposed to pollutants
Sat Jan 01 00:00:00 UTC 2005
Tyrosine phosphorylation of Rab proteins.
Methods in enzymology
Overmeyer JH,Maltese WA
03-7799 was used in western blot investigate tyrosine phosphorylation of Rab proteins
Tue Apr 25 00:00:00 UTC 2006
SIRPbeta1 is expressed as a disulfide-linked homodimer in leukocytes and positively regulates neutrophil transepithelial migration.
The Journal of biological chemistry
Liu Y,Soto I,Tong Q,Chin A,Bühring HJ,Wu T,Zen K,Parkos CA
37700 was used in western blot to characterize expression of signal regulatory proteins in polymorphonuclear leukocytes
Fri Oct 28 00:00:00 UTC 2005
Surface chemistry modulates focal adhesion composition and signaling through changes in integrin binding.
Biomaterials
Keselowsky BG,Collard DM,García AJ
03-7799 was used in immunocytochemistry to study the effects of surface chemistry on focal adhesion assembly and signaling
Wed Dec 01 00:00:00 UTC 2004
Expression of a naturally occurring constitutively active variant of the epidermal growth factor receptor in mouse fibroblasts increases motility.
International journal of cancer
Pedersen MW,Tkach V,Pedersen N,Berezin V,Poulsen HS
03-7799 was used in western blot to study the role of a constitutively active variant of the EGFR in increasing mouse fibroblast motility.
Fri Feb 20 00:00:00 UTC 2004
The C-terminal domain of the heavy chain of tetanus toxin rescues cerebellar granule neurones from apoptotic death: involvement of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways.
Journal of neurochemistry
Chaïb-Oukadour I,Gil C,Aguilera J
03-7700 was used in immunoprecipitation to propose that both PI3K- and ERK-dependent pathways promote cerebellar granule cell survival by the C-terminal domain of the tetanus toxin heavy-chain
Wed Sep 01 00:00:00 UTC 2004
Cocoa procyanidins inhibit proliferation and angiogenic signals in human dermal microvascular endothelial cells following stimulation by low-level H2O2.
Experimental biology and medicine (Maywood, N.J.)
Kenny TP,Keen CL,Jones P,Kung HJ,Schmitz HH,Gershwin ME
37700 was used in western blot to propose that polyphenols modulate endothelial growth signaling
Wed Sep 01 00:00:00 UTC 2004
ErbB3/HER3 does not homodimerize upon neuregulin binding at the cell surface.
FEBS letters
Berger MB,Mendrola JM,Lemmon MA
03-7799 was used in western blot to study oligomerization of ErbB3/HER3
Fri Jul 02 00:00:00 UTC 2004
Activation of EGF receptor kinase by L1-mediated homophilic cell interactions.
Molecular biology of the cell
Islam R,Kristiansen LV,Romani S,Garcia-Alonso L,Hortsch M
03-7700 was used in western blot to demonstrate that L1-type cell adhesion molecules promote the adhesion-dependent activation of EGF receptor signaling
Thu Apr 01 00:00:00 UTC 2004
Recruitment of C-terminal Src kinase by the leukocyte inhibitory receptor CD85j.
Biochemical and biophysical research communications
Sayós J,Martínez-Barriocanal A,Kitzig F,Bellón T,López-Botet M
03-7700 was used in western blot to identify molecules that interact with CD85j
Fri Nov 12 00:00:00 UTC 2004
Heterodimerization with vascular endothelial growth factor receptor-2 (VEGFR-2) is necessary for VEGFR-3 activity.
Biochemical and biophysical research communications
Alam A,Herault JP,Barron P,Favier B,Fons P,Delesque-Touchard N,Senegas I,Laboudie P,Bonnin J,Cassan C,Savi P,Ruggeri B,Carmeliet P,Bono F,Herbert JM
37700 was used in western blot to demonstrate that VEGFR-3 needs to be associated with VEGFR-2 to induce ligand-dependent cellular responses
Fri Nov 12 00:00:00 UTC 2004
Extracellular oxidation by taurine chloramine activates ERK via the epidermal growth factor receptor.
The Journal of biological chemistry
Midwinter RG,Peskin AV,Vissers MC,Winterbourn CC
03-7799 was used in western blot to examine the effects of taurine-chloramine on MAPK signaling in human umbilical vein endothelial cells
Fri Jul 30 00:00:00 UTC 2004
Protein kinase C-related kinase 2 regulates hepatitis C virus RNA polymerase function by phosphorylation.
The Journal of biological chemistry
Kim SJ,Kim JH,Kim YG,Lim HS,Oh JW
03-7799 was used in immunoprecipitation to suggest that hepatitis C viral RNA replication is regulated by NS5B phosphorylation by PRK2
Fri Nov 26 00:00:00 UTC 2004
Misfolding of major histocompatibility complex class I molecules in activated T cells allows cis-interactions with receptors and signaling molecules and is associated with tyrosine phosphorylation.
The Journal of biological chemistry
Santos SG,Powis SJ,Arosa FA
03-7799 was used in western blot to study MHC-I misfolding and expression
Fri Dec 17 00:00:00 UTC 2004
PECAM-1 negatively regulates GPIb/V/IX signaling in murine platelets.
Blood
Rathore V,Stapleton MA,Hillery CA,Montgomery RR,Nichols TC,Merricks EP,Newman DK,Newman PJ
03-7799 was used in western blot to test if PECAM-1 regulates signals emanating from GPIb/FcR gamma.
Sat Nov 15 00:00:00 UTC 2003
Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF.
Proceedings of the National Academy of Sciences of the United States of America
Suzuki N,Nakamura S,Mano H,Kozasa T
03-7799 was used in western blot to elucidate Galpha12-mediated Rho activation.
Tue Jan 21 00:00:00 UTC 2003
Aberrant activation of focal adhesion proteins mediates fibrillar amyloid beta-induced neuronal dystrophy.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Grace EA,Busciglio J
03-7799 was used in immunocytochemistry to elucidate mechanisms that result in fibrillar Abeta-induced neuronal dystrophy.
Wed Jan 15 00:00:00 UTC 2003
Apolipoprotein E (apoE) isoforms differentially induce nitric oxide production in endothelial cells.
FEBS letters
Sacre SM,Stannard AK,Owen JS
37700 was used in western blot to characterize apolipoprotein isoforms to clarify why some are cardioprotective while others contribute to hyperlipidemias
Thu Apr 10 00:00:00 UTC 2003
C-terminal fragment of tetanus toxin heavy chain activates Akt and MEK/ERK signalling pathways in a Trk receptor-dependent manner in cultured cortical neurons.
The Biochemical journal
Gil C,Chaib-Oukadour I,Aguilera J
37700 was used in immunoprecipitation to investigate the activation of PKC isoforms induced by tetanus toxin treatment
Tue Jul 15 00:00:00 UTC 2003
Activation of SRC tyrosine kinases in response to ICAM-1 ligation in pulmonary microvascular endothelial cells.
The Journal of biological chemistry
Wang Q,Pfeiffer GR,Gaarde WA
37700 was used in western blot to determine the role of SRC tyrosine kinases in ICAM-1-initiated signaling using endothelial cells
Fri Nov 28 00:00:00 UTC 2003
Assaying tyrosine phosphorylation of insulin receptor and insulin receptor substrates.
Methods in molecular medicine
Whiteman EL,Birnbaum MJ
Thu Apr 17 00:00:00 UTC 2003
Molecular dissection of the signaling and costimulatory functions of CD150 (SLAM): CD150/SAP binding and CD150-mediated costimulation.
Blood
Howie D,Simarro M,Sayos J,Guirado M,Sancho J,Terhorst C
03-7799 was used in western blot to study the contribution of CD150 to the T cell receptor.
Fri Feb 01 00:00:00 UTC 2002
Localized exocytosis of primary (lysosomal) granules during phagocytosis: role of Ca2+-dependent tyrosine phosphorylation and microtubules.
Journal of immunology (Baltimore, Md. : 1950)
Tapper H,Furuya W,Grinstein S
03-7799 was used in flow cytometry to study delivery of granules toward the forming phagosome.
Wed May 15 00:00:00 UTC 2002
Inhibition of epidermal growth factor receptor-mediated signaling by "Combi-triazene" BJ2000, a new probe for Combi-Targeting postulates.
The Journal of pharmacology and experimental therapeutics
Brahimi F,Matheson SL,Dudouit F,McNamee JP,Tari AM,Jean-Claude BJ
03-7799 was used in Western Blotting to determine whether the epidermal growth factor receptor (EGFR) affinity of the combi-molecule and that of its hydrolytic metabolites are critical parameters for sustained potency against EGFR-overexpressing cells.
Tue Oct 01 00:00:00 UTC 2002
Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75.
Neuroscience
Culmsee C,Gerling N,Lehmann M,Nikolova-Karakashian M,Prehn JH,Mattson MP,Krieglstein J
03-7799 was used in immunocytochemistry to investigate the role of the common neurotrophin receptor p75 in neuronal survival and cell death
Wed Mar 12 00:00:00 UTC 2003
Cloning of two new splice variants of Siglec-10 and mapping of the interaction between Siglec-10 and SHP-1.
Biochemical and biophysical research communications
Kitzig F,Martinez-Barriocanal A,López-Botet M,Sayós J
03-7799 was used in western blot to clone and characterize a new splice variant of Siglec-10.
Fri Aug 16 00:00:00 UTC 2002
Direct identification of tyrosine 474 as a regulatory phosphorylation site for the Akt protein kinase.
The Journal of biological chemistry
Conus NM,Hannan KM,Cristiano BE,Hemmings BA,Pearson RB
03-7799 was used in western blot to investigate regulation of Akt.
Fri Oct 11 00:00:00 UTC 2002
Structural requirements for interaction of sodium channel beta 1 subunits with ankyrin.
The Journal of biological chemistry
Malhotra JD,Koopmann MC,Kazen-Gillespie KA,Fettman N,Hortsch M,Isom LL
03-7799 was used in western blot to test if a tyrosine residue in the cytoplasmic domain of beta 1 is important for ankyrin recruitment.
Fri Jul 19 00:00:00 UTC 2002
CD44 stimulation by fragmented hyaluronic acid induces upregulation and tyrosine phosphorylation of c-Met receptor protein in human chondrosarcoma cells.
Biochimica et biophysica acta
Suzuki M,Kobayashi H,Kanayama N,Nishida T,Takigawa M,Terao T
03-7700 was used in western blot to demonstrate that CD44 stimulation enhances c-Met expression and tyrosine phosphorylation in human chondrosarcoma cells
Mon Aug 19 00:00:00 UTC 2002
HC fragment (C-terminal portion of the heavy chain) of tetanus toxin activates protein kinase C isoforms and phosphoproteins involved in signal transduction.
The Biochemical journal
Gil C,Chaib-Oukadour I,Blasi J,Aguilera J
37700 was used in immunoprecipitation to elucidate the host signaling pathways altered by tetanus toxin
Tue May 15 00:00:00 UTC 2001
Modulation of nicotinic acetylcholine receptor turnover by tyrosine phosphorylation in rat myotubes.
Neuroscience letters
Sava A,Barisone I,Di Mauro D,Fumagalli G,Sala C
03-7799 was used in immunoprecipitation to test if tyrosine phosphorylation modulates the turnover of the acetylcholine receptor
Fri Nov 02 00:00:00 UTC 2001
Indirect role for COPI in the completion of FCgamma receptor-mediated phagocytosis.
The Journal of biological chemistry
Hackam DJ,Botelho RJ,Sjolin C,Rotstein OD,Robinson JM,Schreiber AD,Grinstein S
03-7799 was used in immunocytochemistry to test if COPI is involved in phagosome formation
Fri May 25 00:00:00 UTC 2001
Stimulation of receptor-mediated nitric oxide production by vanadate.
Arteriosclerosis, thrombosis, and vascular biology
Hellermann GR,Flam BR,Eichler DC,Solomonson LP
03-7700 was used in western blot to demonstrate a link between tyrosine phosphorylation and stimulation of endothelial nitric oxide production
Fri Sep 01 00:00:00 UTC 2000
Potential pathways for regulation of NK and T cell responses: differential X-linked lymphoproliferative syndrome gene product SAP interactions with SLAM and 2B4.
International immunology
Sayós J,Nguyen KB,Wu C,Stepp SE,Howie D,Schatzle JD,Kumar V,Biron CA,Terhorst C
03-7700 was used in western blot to examine the SAP gene in natural killer cells
Fri Dec 01 00:00:00 UTC 2000
5' phospholipid phosphatase SHIP-2 causes protein kinase B inactivation and cell cycle arrest in glioblastoma cells.
Molecular and cellular biology
Taylor V,Wong M,Brandts C,Reilly L,Dean NM,Cowsert LM,Moodie S,Stokoe D
03-7700 was used in western blot to propose that SHIP-2 plays a negative role in regulating the PI3K-PKB pathway
Fri Sep 01 00:00:00 UTC 2000
Activation of signal transduction pathways involving trkA, PLCgamma-1, PKC isoforms and ERK-1/2 by tetanus toxin.
FEBS letters
Gil C,Chaïb-Oukadour I,Pelliccioni P,Aguilera J
03-7700 was used in western blot to demonstrate the differential activation of PKC isoforms and of signal transduction pathways by tetanus toxin in a synaptosome-enriched P(2) fraction from rat brain
Fri Sep 15 00:00:00 UTC 2000
Cryptosporidium parvum induces host cell actin accumulation at the host-parasite interface.
Infection and immunity
Elliott DA,Clark DP
03-7700 was used in immunocytochemistry to investigate how Cryptosporidium induces rearrangement of the host cell cytoskeleton to form the host-parasite junctional complex
Sat Apr 01 00:00:00 UTC 2000
Characterization of the tyrosine kinases RAFTK/Pyk2 and FAK in nerve growth factor-induced neuronal differentiation.
The Journal of biological chemistry
Park SY,Avraham H,Avraham S
03-7799 was used in Western Blot to investigate related adhesion focal tyrosine kinase and focal adhesion kinase signalling upon nerve growth factor stimulation of PC12 cells.
Fri Jun 30 00:00:00 UTC 2000
A new role for platelet-endothelial cell adhesion molecule-1 (CD31): inhibition of TCR-mediated signal transduction.
Journal of immunology (Baltimore, Md. : 1950)
Newton-Nash DK,Newman PJ
03-7799 was used in western blot to test if PECAM-1 inhibits protein tyrosine kinase-dependent signal transduction.
Thu Jul 15 00:00:00 UTC 1999
Alloantibody-mediated class I signal transduction in endothelial cells and smooth muscle cells: enhancement by IFN-gamma and TNF-alpha.
Journal of immunology (Baltimore, Md. : 1950)
Bian H,Reed EF
03-7799 was used in western blot to test if anti-HLA Abs transduce signals via HLA class I molecules and stimulate cell proliferation.
Thu Jul 15 00:00:00 UTC 1999
Ligation of HLA class I molecules on smooth muscle cells with anti-HLA antibodies induces tyrosine phosphorylation, fibroblast growth factor receptor expression and cell proliferation.
International immunology
Bian H,Harris PE,Reed EF
03-7799 was used in western blot to elucidate the role of anti-donor HLA antibodies in transplant atherosclerosis.
Tue Sep 01 00:00:00 UTC 1998
NMDA receptor and the tyrosine phosphorylation of its 2B subunit in taste learning in the rat insular cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Rosenblum K,Berman DE,Hazvi S,Lamprecht R,Dudai Y
03-7799 was used in western blot to elucidate the role of the NMDA receptor in taste learning.
Tue Jul 01 00:00:00 UTC 1997
The type II transforming growth factor-beta receptor autophosphorylates not only on serine and threonine but also on tyrosine residues.
The Journal of biological chemistry
Lawler S,Feng XH,Chen RH,Maruoka EM,Turck CW,Griswold-Prenner I,Derynck R
03-7799 was used in western blot to elucidate the initial events in TGF-beta signaling.
Fri Jun 06 00:00:00 UTC 1997
The intracellular signal transduction mechanism of interleukin 5 in eosinophils: the involvement of lyn tyrosine kinase and the Ras-Raf-1-MEK-microtubule-associated protein kinase pathway.
The Journal of experimental medicine
Pazdrak K,Schreiber D,Forsythe P,Justement L,Alam R
03-7799 was used in western blot to elucidate the intracellular signal transduction mechanism of IL-5 in eosinophils.
Mon May 01 00:00:00 UTC 1995
Overexpressed Csk tyrosine kinase is localized in focal adhesions, causes reorganization of alpha v beta 5 integrin, and interferes with HeLa cell spreading.
Molecular and cellular biology
Bergman M,Joukov V,Virtanen I,Alitalo K
03-7799 was used in immunocytochemistry, immunoprecipitation, and western blot to investigate the role of Csk.
Wed Feb 01 00:00:00 UTC 1995
pp125FAK in human melanocytes and melanoma: expression and phosphorylation.
Experimental cell research
Scott G,Liang H
03-7799 was used in western blot to study pp125FAK phosphorylation in human melanocytes and melanoma cells.
Sat Jul 01 00:00:00 UTC 1995
Transcription factor ISGF-3 formation requires phosphorylated Stat91 protein, but Stat113 protein is phosphorylated independently of Stat91 protein.
Proceedings of the National Academy of Sciences of the United States of America
Improta T,Schindler C,Horvath CM,Kerr IM,Stark GR,Darnell JE
03-7799 was used in western blot to determine the effects of phosphorylation on formation of the transcription factor ISGF-3.
Tue May 24 00:00:00 UTC 1994
The extracellular matrix as a cell survival factor.
Molecular biology of the cell
Meredith JE,Fazeli B,Schwartz MA
03-7799 was used in western blot to test if the extracellular matrix is a cell survival factor.
Wed Sep 01 00:00:00 UTC 1993
