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Invitrogen
Phospho-VAV1 (Tyr160) Polyclonal Antibody
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Product Details
PA1-26651
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic phosphopeptide corresponding to a portion of human VAV 1 containing tyrosine 160. The sequence is conserved in mouse and rat.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2213566
Product Specific Information
PA1-26651 detects VAV1 (phospho Y160) from human samples. PA1-26651 is expected to cross react with mouse, rat, and a wide range of other species due to sequence homology.
PA1-26651 has been successfully used in Western blot procedures.
The PA1-26651 immunogen is a synthetic phosphopeptide corresponding to a portion of human VAV 1 containing tyrosine 160. The sequence is conserved in mouse and rat.
Target Information
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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