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Invitrogen
Phospho-TCF3 (Thr355) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-TCF3 (Thr355) Antibody (PA1-20230) in WB
Western blot analysis of Phospho-TCF3 pThr355 using whole cell lysate from 293T cells that were transfected with an expression construct that encoded wild-type E2A (E47) or S352A/T355A/S359A mutant E2A (Mm). Samples were probed with a Phospho-TCF3 pThr355 polyclonal antibody (Product # PA1-20230) at a dilution of 0.1µg/ml. Detection was performed using chemiluminescence with an exposure time of less than 5 ... View More
Product Details
PA1-20230
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic phosphopeptide corresponding to human E2A immunoglobulin enhancer binding factors E12/E47 around threonine 355.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Storage conditions
4°C, do not freeze
Shipping conditions
Wet ice
Product Specific Information
PA1-20230 detects Phospho-TCF3 (pT355) in human samples.
PA1-20230 has been successfully used in Western blot procedures.
The PA1-20230 immunogen is a synthetic phosphopeptide corresponding to human E2A immunoglobulin enhancer binding factors E12/E47 around threonine 355 (LocusLinkID 6929).
Target Information
TCF3 (E2A) is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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