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Invitrogen
Phospho-JNK1 + JNK2 (Thr183, Tyr185) Polyclonal Antibody
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Product Details
OPA1-03075
Applications
Tested Dilution
Publications
Product Specifications
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic phosphopeptide derived from human JNK 1 and 2 that contains threonine 183 and tyrosine 185.
Conjugate
Form
Liquid
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
OPA1-03075 detects cJun N-terminal kinase (JNK) from human and rat tissues and cells.
OPA1-03075 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~49 kDa protein and an ~55 kDa protein representing JNK1 and 2, respectively, from platelet-derived growth factor (PDGF) treated NIH-3T3 cell extract.
OPA1-03075 immunizing phosphopeptide was derived from human JNK 1 and 2 that contains threonine 183 and tyrosine 185. This region is conserved among many species including mouse, rat, chicken, nematode, fruit fly, and in JNK3.
Target Information
C-Jun N-terminal Kinase (JNK) is also known as Mitogen-activated protein kinase (MAPK8). It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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