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PA5-34980 targets Phospho-HEC1 pSer55 in ICC, IF, IP, ELISA and WB applications and shows reactivity with Human, Mouse, and Rat samples.
The PA5-34980 immunogen is synthetic phosphopeptide corresponding to the amino acids around Ser 55 conjugated to KLH.
Hec1 is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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