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PA1-26723 detects Dab1 (phospho Y198) from human and mouse samples. PA1-26723 is expected to cross react with chicken (100% conserved) and rat (100% conserved) due to sequence homology.
PA1-26723 has been successfully used in Western blot procedures.
The PA1-26723 immunogen is a synthetic phosphopeptide corresponding to a portion of human Dab1 containing tyrosine 198.
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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