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Invitrogen
Phospho-Caveolin-1 (Tyr14) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-Caveolin-1 (Tyr14) Antibody (PA5-35601) in WB
Western blot analysis of Phospho-Caveolin-1 pTyr14 in H2O2-treated NIH-3T3 whole cell lysates with a blocking peptide (lane 1) and no blocking peptide (lane 2) using a Phospho-Caveolin-1 pTyr14 polyclonal antibody (Product # PA5-35601).
Product Details
PA5-35601
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide derived from human Caveolin-1 around the phosphorylation site of Tyrosine 14
Conjugate
Form
Liquid
Concentration
Lot-Specific
Storage conditions
-20°C
Shipping conditions
Ambient
RRID
AB_2552911
Product Specific Information
Concentration is lot-specific and will vary from 0.5-0.6 mg/ml
Target Information
Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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