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MA1-10745 detects Phenobarbital.
MA1-10745 has been successfully used in ELISA applications.
The MA1-10745 immunogen is Phenobarbital, conjugated to KLH.
Phenobarbital is a long-acting barbituric acid derivative with antipsychotic property. Phenobarbital binds to and activates the gamma-aminobutyric acid (GABA)-A receptor, thereby mimicking the inhibitory actions of GABA in the brain. The activation effects of the phenobarbital-receptor-ionophore complex include increased frequency of chloride channel openings, membrane hyperpolarization and ultimately synaptic inhibition and decreased neuronal excitability. In addition, this agent inhibits glutamate induced depolarization. [National Center for Biotechnology Information. PubChem Compound Database; CID=4763].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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