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Invitrogen
PTPRN2 Polyclonal Antibody
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Product Details
PA5-50110
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from internal of human PTPRN2 (aa 206-255).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2635563
Product Specific Information
The antibody detects endogenous levels of total PTPRN2 protein.
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 3.1.3.48; IA-2 beta; IAR; IAR/receptor-like protein-tyrosine phosphatase; Islet cell autoantigen-related protein; Phogrin; protein tyrosine phosphatase receptor pi; protein tyrosine phosphatase, receptor type, N polypeptide 2; Protein tyrosine phosphatase-NP; PTP IA-2beta; PTP-NP; R-PTP-N2; Receptor-type tyrosine-protein phosphatase N2; tyrosine phosphatase IA-2 beta
Gene Aliases: 4930425H11Rik; IA-2beta; IA2beta; IAR; ICAAR; KIAA0387; mKIAA0387; phogrin; Phol; PTP-NP; PTPRN2; PTPRP; R-PTP-N2
UniProt ID: (Human) Q92932, (Mouse) P80560
Entrez Gene ID: (Human) 5799, (Mouse) 19276
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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