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Invitrogen
PSMD11 Polyclonal Antibody
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FIGURE: 1 / 4
PSMD11 Antibody (PA5-27447) in ICC/IF
Immunofluorescent analysis of PSMD11 showing staining in the nucleus and cytoplasm of A549 cells. A549 cells were fixed in 4% paraformaldehyde at RT for 15 min and stained using a PSMD11 polyclonal antibody (Product # PA5-27447) diluted at 1:500. Blue: Hoechst 33342 staining.
Product Details
PA5-27447
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 266 and 422 of Human PSMD11
Conjugate
Form
Liquid
Concentration
0.68 mg/mL
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2544923
Product Specific Information
PA5-27447 targets PSMD11 in WB applications and shows reactivity with Human samples.
The PA5-27447 immunogen is recombinant fragment corresponding to a region within amino acids 266 and 422 of Human PSMD11.
Target Information
The 26S proteasome (PSMD11) is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The protein is a non-ATPase subunit of the 19S regulator.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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