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Invitrogen
PRTFDC1 Monoclonal Antibody (06)
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FIGURE: 1 / 1
PRTFDC1 Antibody (MA5-36034) in WB
Western Blot analysis of PRTFDC1 using PRTFDC1 Monoclonal Antibody (Product # MA5-36034) at a dilution of 1:500. Lane A: 293T whole cell lysate, (Lysates/proteins at 30 µg per lane). The secondary antibody used was a Goat Anti-Mouse IgG H&L (Dylight800) at 1:15,000 dilution. Developed using the Odyssey technique and performed under reducing conditions. Predicted band size: 26 kDa. Observed band size: 26 kDa.
Product Details
MA5-36034
Product Specifications
Host/Isotype
Mouse
/ IgG
Class
Monoclonal
Type
Antibody
Clone
06
Immunogen
Recombinant Human PRTFDC1 protein
Conjugate
Form
Liquid
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2866646
Target Information
Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene. Recently, it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays, while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth. These results suggest that PRTFDC1 can act as a tumor-suppressor gene. At least three isoforms of PRTFDC1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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