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Invitrogen
PROK2 Polyclonal Antibody
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Product Details
PA5-59557
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PROK2
Conjugate
Form
Liquid
Concentration
Lot-Specific
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2645957
Product Specific Information
Immunogen sequence: TCPCLPGLAC LRTSFNRFIC LAQ
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
Target Information
Prokineticin-2 (PK2) is a cysteine-rich secreted protein that is expressed in the suprachiasmatic nucleus (SCN) with receptors located in the critical autonomic control centers of the brain. It has a depolarizing effect on neurons expressing the receptor. PK2 is predominantly controlled by the endogenous circadian clock, but light also plays a modulatory role. PK2 functions as a critical SCN output molecule responsible for circadian locomotor rhythms. PK2 expression is high during the day, and responsive to nocturnal light pulses. PK2 also functions as a chemoattractant for subventricular zone-derived neuronal progenitors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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