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Invitrogen
PRICKLE1 Polyclonal Antibody
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FIGURE: 1 / 2
PRICKLE1 Antibody (PA5-51570) in IHC
eLife 2020 -
Figure 5. FOXC1 and FOXC2 mediate lymphatic expression of the PCP signaling component and RHOA signaling regulator Prickle1. ( a ) Reduced expression of Prickle1 , Arhgap21 , and Arhgap23 in Foxc1/c2 -compound mutant LECs isolated from the dorsal skin at E15.5. Graph shows RPKM values from RNA-seq analysis. *** denotes p<0.001. ( b, c ) Putative FOX-binding sites in regions of the human PRICKLE1... View More
Product Details
PA5-51570
Applications
Tested Dilution
Publications
Product Specifications
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PRICKLE1
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2645937
Product Specific Information
Immunogen sequence: GASGYNHDET QWYEDSLECL SDLKPEQSVR DSMDSLALSN ITGASVDGEN KPRPSLYSLQ NFEEMETEDC EKMSNMGTLN SSMLHRSAES LKSLSSELCP EKILPEEKPV HLPVLRRSKS QSRPQQVKFS DDVIDNGNYD IEI
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 94%.
Target Information
Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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