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Invitrogen
PPY Polyclonal Antibody
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Product Details
PA1-36141
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Pure bovine pancreatic polypeptide.
Conjugate
Form
Lyophilized
Storage conditions
4°C
Shipping conditions
Wet ice
Product Specific Information
Suggested positive controls for IHC include paraffin sections of pig duodenal pancreas and frozen sections of rat pancreas.
Reconstitute with 50-100 ul of distilled water, and dilute further in 0.1M PBS with 1% BSA and 0.1% sodium azide. For long-term storage, aliquot and store at -20°C.
Target Information
Pancreatic polypeptide (PP) is a 36 amino-acid residue peptide with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and was the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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