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Abnova
PPFIBP2 Monoclonal Antibody (3A5)
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Product Details
H00008495-M02
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
3A5
Immunogen
PPFIBP2 (NP_003612, 1 a.a. approximately 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MASDASHALE AALEQMDGII AGTKTGADLS DGTCEPGLAS PASYMNPFPV LHLIEDLRLA LEMLELPQER AALLSQIPGP TAAYIKEWFE ESLSQVNHHS
Target Information
The PPFIBP2 (PPFIA Binding Protein 2) gene encodes a protein that belongs to the liprin family, which is involved in intracellular signaling and cytoskeletal organization. Located on chromosome 1, PPFIBP2 is primarily known for its role in synaptic function and cell adhesion. The protein interacts with receptor protein tyrosine phosphatases, particularly PTPRF and PTPRD, and plays a critical role in the formation and maintenance of synaptic contacts. PPFIBP2 facilitates the proper localization of synaptic vesicles and synapse-specific proteins, contributing to synaptic stability and plasticity. Disruption of PPFIBP2 expression or function has been linked to neurological disorders, emphasizing its importance in neural communication. Additionally, PPFIBP2 has been implicated in cancer, where it may influence tumor cell adhesion and migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: liprin beta 2; Liprin-beta-2; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2; PTPRF interacting protein, binding protein 2 (liprin beta 2); PTPRF-interacting protein-binding protein 2
Gene Aliases: Cclp1; PPFIBP2
UniProt ID: (Human) Q8ND30
Entrez Gene ID: (Human) 8495
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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