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Abnova
PPFIBP2 Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 1
PPFIBP2 Antibody (H00008495-D01P) in WB
Western Blot analysis of PPFIBP2 expression in transfected 293T cell line (H00008495-T02) by PPFIBP2 MaxPab polyclonal antibody.
Lane 1: PPFIBP2 transfected lysate(98.40 KDa).
Lane 2: Non-transfected lysate.
Lane 1: PPFIBP2 transfected lysate(98.40 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00008495-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PPFIBP2 (NP_003612.1, 1 a.a. approximately 876 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MASDASHALE AALEQMDGII AGTKTGADLS DGTCEPGLAS PASYMNPFPV LHLIEDLRLA LEMLELPQER AALLSQIPGP TAAYIKEWFE ESLSQVNHHS AASNETYQER LARLEGDKES LILQVSVITD QVEAQGEKIR DLEVCLEGHQ VKLNAAEEML QQELLSRTSL ETQKLDLMTE VSELKLKLVG MEKEQREQEE KQRKAEELLQ ELRHLKIKVE ELENERNQYE WKLKATKAEV AQLQEQVALK DAEIERLHSQ LSRTAALHSE SHTERDQEIQ RLKMGMETLL LANEDKDRRI EELTGLLNQY RKVKEIVMVT QGPSERTLSI NEEEPEGGFS KWNATNKDPE ELFKQEMPPR CSSPTVGPPP LPQKSLETRA QKKLSCSLED LRSESVDKCM DGNQPFPVLE PKDSPFLAEH KYPTLPGKLS GATPNGEAAK SPPTICQPDA TGSSLLRLRD TESGWDDTAV VNDLSSTSSG TESGPQSPLT PDGKRNPKGI KKFWGKIRRT QSGNFYTDTL GMAEFRRGGL RATAGPRLSR TRDSKGQKSD ANAPFAQWST ERVCAWLEDF GLAQYVIFAR QWVSSGHTLL TATPQDMEKE LGIKHPLHRK KLVLAVKAIN TKQEEKSALL DHIWVTRWLD DIGLPQYKDQ FHESRVDGRM LQYLTVNDLL FLKVTSQLHH LSIKCAIHVL HVNKFNPHCL HRRPADESNL SPSEVVQWSN HRVMEWLRSV DLAEYAPNLR GSGVHGGLII LEPRFTGDTL AMLLNIPPQK TLLRRHLTTK FNALIGPEAE QEKREKMASP AYTPLTTTAK VRPRKLGFSH FGNIRKKKFD ESTDYICPME PSDGVSDSHR VYSGYRGLSP LDAPELDGLD QVGQIS
Target Information
The PPFIBP2 (PPFIA Binding Protein 2) gene encodes a protein that belongs to the liprin family, which is involved in intracellular signaling and cytoskeletal organization. Located on chromosome 1, PPFIBP2 is primarily known for its role in synaptic function and cell adhesion. The protein interacts with receptor protein tyrosine phosphatases, particularly PTPRF and PTPRD, and plays a critical role in the formation and maintenance of synaptic contacts. PPFIBP2 facilitates the proper localization of synaptic vesicles and synapse-specific proteins, contributing to synaptic stability and plasticity. Disruption of PPFIBP2 expression or function has been linked to neurological disorders, emphasizing its importance in neural communication. Additionally, PPFIBP2 has been implicated in cancer, where it may influence tumor cell adhesion and migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: liprin beta 2; Liprin-beta-2; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2; PTPRF interacting protein, binding protein 2 (liprin beta 2); PTPRF-interacting protein-binding protein 2
Gene Aliases: Cclp1; PPFIBP2
UniProt ID: (Human) Q8ND30
Entrez Gene ID: (Human) 8495
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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