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Abnova
POU6F1 Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 1
POU6F1 Antibody (H00005463-D01P) in WB
Western Blot analysis of POU6F1 expression in transfected 293T cell line (H00005463-T01) by POU6F1 MaxPab polyclonal antibody.
Lane 1: POU6F1 transfected lysate(32.60 KDa).
Lane 2: Non-transfected lysate.
Lane 1: POU6F1 transfected lysate(32.60 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00005463-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
POU6F1 (AAH74765.3, 1 a.a. approximately 301 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MPGISSQILT NAQGQVIGTL PWVVNSASVA APAPAQSLQV QAVTPQLLLN AQGQVIATLA SSPLPPPVAV RKPSTPESPA KSEVQPIQPT PTVPQPAVVI ASPAPAAKPS ASAPIPITCS ETPTVSQLVS KPHTPSLDED GINLEEIREF AKNFKIRRLS LGLTQTQVGQ ALTATEGPAY SQSAICRFEK LDITPKSAQK LKPVLEKWLN EAELRNQEGQ QNLMEFVGGE PSKKRKRRTS FTPQAIEALN AYFEKNPLPT GQEITEIAKE LNYDREVVRV WFCNRRQTLK NTSKLNVFQI P
Target Information
Brn-5 (Brain-5), also known as POU6F1, MPOU or TCFB1, is a widely expressed protein but during embryogenesis is exclusively found in the developing brain and spinal cord. As is characteristic of Brn family members, Brn-5 contains two DNA-binding domains, namely the POU-specific domain and the POU homeodomain, which each contain an HTH (helix-turn-helix) motif. Brn-5 binds to CRH (corticotrophin-releasing hormone) elements with high affinity and is capable of both enhancing Prolactin gene expression and activating Pit-1 expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brain-5; Brain-specific homeobox/POU domain protein 5; brn-5; mPOU homeobox protein; POU domain, class 6, transcription factor 1
Gene Aliases: BRN5; MPOU; POU6F1; TCFB1
UniProt ID: (Human) Q14863
Entrez Gene ID: (Human) 5463
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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