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Search Thermo Fisher Scientific
Proteintech
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Immunogen sequence: PEGLTSTSL LDLLLPTGLE PLDSEEPSET MGLGAGLGAP GSGFPSEENE ESRILQPPQY FWEEEEELND SSLDLGPTAD YVFPDLTEKA GSIEDTSQAQ ELPNLPSPLP KMNLVEPPWH MPPREEEEEE EEEEEREKEE VEKQEEEEEE ELLPVNGSQE EAKPQVRDFS LTSSSQTPGA TKSRHEDSGD QASSGVEVES SMGPSLLLPS VTPTTVTPGD QDSTSQEAEA TVLPAAGLGV EFEAPQEASE EATAGAAGLS GQHEEVPALP SFPQTTAPSG AEHPDEDPLG SRTSASSPQL LALVEEVLPR HGSGHHGAWH ISLSKPSEKE QHLLMTLVGE QGVVPTQDVL SMLGDIRRSL EEIGIQNYST TSSCQARASQ VRSDY (39-422 aa encoded by B C019330)
Podolyxin is a CD34 family member expressed by podocytes, vascular endothelium, mesothelium, and a subset of hematopoietic progenitors. It is the major sialoprotein in the glycocalyx of glomerular podocytes. The physiologic role of podolyxin in leukemic blasts is unknown. However, it is thought of as a candidate prostate cancer tumor aggressiveness gene. Podolyxin appears to complement CD34 as a useful cell surface marker for hemangioblasts, the common precursors of hematopoietic and endothelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Endoglycan; podocalyxin-like 2; Podocalyxin-like protein 2
Gene Aliases: D130074J02Rik; EG; PODLX2; PODXL2; RGD1305815; UNQ1861/PRO3742
UniProt ID: (Human) Q9NZ53, (Mouse) Q8CAE9
Entrez Gene ID: (Human) 50512, (Rat) 297433, (Mouse) 319655
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