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Invitrogen
PNK Polyclonal Antibody
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FIGURE: 1 / 1
PNK Antibody (PA1-29915) in WB
Western blot analysis of PNK in yeast extract (lane 1) and yeast extract + AD-PNK human fusion protein using a PNK polyclonal antibody (Product # PA1-29915) at a dilution of 1:1000 after incubation for 1hr in TBST. The AD fusion is an Activation Domain fusion protein. The band representing PNK is marked by the arrow.
Product Details
PA1-29915
Product Specifications
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence EPRLGRLYCQFSEG, from C Terminus of the protein sequence according to NP_009185.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_1959855
Product Specific Information
PA1-29915 detects PNK from human samples.
PA1-29915 has been successfully used in Western blot applications.
The PA1-29915 immunogen is: Peptide with sequence EPRLGRLYCQFSEG, from C Terminus of the protein sequence according to NP_009185.
Target Information
Anti-human Polynucleotide Kinase Mouse Monoclonal Antibody recognizes polynucleotide kinase (PNK), a 57 kDa nuclear enzyme implicated in DNA strand repair processes that occur during DNA replication and recombination, or in response to DNA damaging agents. PNK targets the DNA 5'-hydroxy and 3'-phosphate termini for phosphorylation and dephosphorylation events. During strand breakage in human cells, normal PNK associates with other nuclear proteins to prepare the DNA termini for the enzymatic actions of DNA polymerase-beta and DNA ligase III. PNK is a key functional component in maintaining the genetic stability of human cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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