Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
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FIGURE: 1 / 2
Recommended positive controls: HeLa, Jurkat, NT2D1, mouse liver.
Predicted reactivity: Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The PLEKHJ1 (Pleckstrin Homology Domain Containing, Family J Member 1) gene encodes a protein that is involved in signal transduction and cytoskeletal organization. Located on chromosome 11, the PLEKHJ1 protein contains a pleckstrin homology (PH) domain, which facilitates its binding to phosphoinositides and the subsequent interaction with cellular membranes. This interaction is vital for various cellular processes, including the regulation of cell shape, motility, and intracellular trafficking. The precise biological functions of PLEKHJ1 are still being elucidated, but its role in these signaling pathways underscores its importance in maintaining cellular architecture and function. Alterations in PLEKHJ1 expression or mutations can have significant implications for cellular dynamics and have been linked to certain pathological conditions, including cancer.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: guanine nucleotide releasing protein x; Guanine nucleotide-releasing protein x; PH domain-containing family J member 1; pleckstrin homology domain containing, family J member 1; Pleckstrin homology domain-containing family J member 1
Gene Aliases: 9530063M10Rik; GNRPX; PLEKHJ1
UniProt ID: (Human) Q9NW61, (Mouse) Q9D240
Entrez Gene ID: (Human) 55111, (Mouse) 78670
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