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Proteintech
PLEKHG5 Polyclonal Antibody
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Product Details
19830-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PLEKHG5 Fusion Protein Ag11725 (597-930 aa encoded by BC015231)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: KDSKMDVYC FLFTDLLLVT KAVKKAERTR VIRPPLLVDK IVCRELRDPG SFLLIYLNEF HSAVGAYTFQ ASGQALCRGW VDTIYNAQNQ LQQLRAQEPP GSQQPLQSLE EEEDEQEEEE EEEEEEEEGE DSGTSAASSP TIMRKSSGSP DSQHCASDGS TETLAMVVVE PGDTLSSPEF DSGPFSSQSD ETSLSTTASS ATPTSELLPL GPVDGRSCSM DSAYGTLSPT SLQDFVAPGP MAELVPRAPE SPRVPSPPPS PRLRRRTPVQ LLSCPPHLLK SKSEASLLQL LAGAGTHGTP SAPSRSLSEL CLAVPAPAQE ADPGPALPNQ DHPAA (597-930 aa encoded by BC015231)
Target Information
Guanine nucleotide exchange factor that activates RHOA and maybe the NF-kappa-B signaling pathway. Involved in the control of neuronal cell differentiation. Plays a role in angiogenesis through regulation of endothelial cells chemotaxis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GEF720; Guanine nucleotide exchange factor 720; Neuronal RhoA GEF protein; NFkB activating protein; novel PH domain-containing protein; PH domain-containing family G member 5; pleckstrin homology domain containing family G member 5; pleckstrin homology domain containing, family G (with RhoGef domain) member 5; Pleckstrin homology domain-containing family G member 5; RhoA-specific guanine exchange factor SYX1; RhoA-specific guanine exchange factor SYX2; synectin-binding guanine exchange factor; Synectin-binding RhoA exchange factor; SYX; Transcript highly enriched in cortex and hippocampus
Gene Aliases: BC023181; CMTRIC; DSMA4; GEF720; KIAA0720; PLEKHG5; Syx; Tech
UniProt ID: (Human) O94827, (Rat) Q6RFZ7, (Mouse) Q66T02
Entrez Gene ID: (Human) 57449, (Rat) 310999, (Mouse) 269608
signal transduction
regulation of Rho protein signal transduction
endothelial cell chemotaxis
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
endothelial cell migration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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