Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Abnova
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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MFPQNAKPGF KHAGSEGELY PPESQPPVSG SAPPEDLEDA GPPTLDPSGT SITEEILELL NQRGLRDPGP STHDIPKFPG DSQVPGDSET LTFQALPSRD SSEEEEEEEE GLEMDERGPS PLHVLEGLES SIAAEMPSIP CLTKIPDVPN LPEIPSHCEI PEGSRLPSLS DISDVFEMPC LPAIPSVPNT PSLSSTPTLS CDSWLQGPLQ EPAEAPATRR ELFSGSNPGK LGEPPSGGKA GPEEDEEGVS FTDFQPQDVT QHQGFPDELA FRSCSEIRSA WQALEQGQLA RPGFPEPLLI LEDSDLGGDS GSGKAGAPSS ERTASRVREL ARLYSERIQQ MQRAETRASA NAPRRRPRVL AQPQPSPCLP QEQAEPGLLP AFGHVLVCEL AFPLTCAQES VPLGPAVWVQ AAIPLSKQGG SPDGQGLHVS NLPKQDLPGI HVSAATLLPE QGGSRHVQAP AATPLPKQEG PLHLQVPALT TFSDQGHPEI QVPATTPLPE HKSHMVIPAP STAFCPEQGH CADIHVPTTP ALPKEICSDF TVSVTTPVPK QEGHLDSESP TNIPLTKQGG SRDVQGPDPV CSQPIQPLSW HGSSLDPQGP GDTLPPLPCH LPDLQIPGTS PLPAHGSHLD HRIPANAPLS LSQELPDTQV PATTPLPLPQ VLTDIWVQAL PTSPKQGSLP DIQGPAAAPP LPEPSLTDTQ VQKLTPSLEQ KSLIDAHVPA ATPLPERGGS LDIQGLSPTP VQTTMVLSKP GGSLASHVAR LESSDLTPPH SPPPSSRQLL GPNAAALSRY LAASYISQSL ARRQGPGGGA PAASRGSWSS APTSRASSPP PQPQPPPPAA RRLSYATTVN IHVGGGGRLR PAKAQVRLNH PALLASTQES MGLHRAQGAP DAPFHM
PLEKHG2 may be a transforming oncogene with exchange activity for CDC42. PLEKHG2 may be a guanine-nucleotide exchange factor (GEF) for RAC1 and CDC42.PLEKHG2 activated by the binding to subunits beta and gamma of the heterotrimeric guanine nucleotide-binding protein (G protein).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: common-site lymphoma/leukemia guanine nucleotide exchange factor; CTB-60E11.4; DKFZp667J2325; FLJ00018; FLJ22458; FLJ38638; PH domain-containing family G member 2; pleckstrin homology domain containing, family G (with RhoGef domain) member 2; Pleckstrin homology domain-containing family G member 2
Gene Aliases: ARHGEF42; CLG; LDAMD; PLEKHG2
UniProt ID: (Human) Q9H7P9
Entrez Gene ID: (Human) 64857
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