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AbboMax
PLAC1 Polyclonal Antibody
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PLAC1 Antibody (620-390) in IHC (P)
Immunohistochemistry: Human Colon Carcinoma tissue (FFPE) stained with Rabbit Anti-PLAC1 antibody (Cat# 620-390) at 1:200 for 10 min @ RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
Product Details
620-390
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to the internal sequence of human Placenta-specific 1 protein (180-200aa and 160- 180aa)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with proprietary stabilizer
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
Product Specific Information
Positive control: HepG2
Cellular location: membrane.
Target Information
PLAC1 was initially identified as a protein expressed specifically in the placenta and other cells derived from the trophoblast lineage during embryonic development, but has also been found to be expressed ectopically in a wide range of human malignancies, particularly breast cancers. PLAC1 is a membrane-associated protein that is thought to serve a receptor-like function modulating cell-cell or ligand receptor interactions unique to the maternal-placental interface. Decreased expression of PLAC1 is associated with decreased expression of cyclin D1 and reduced expression of AKT kinase, which, combined with the fact that PLAC1 is expressed on the surface of cancer cells, suggests that PLAC1 may be an effective candidate for immunotherapeutic treatments of cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cancer/testis antigen 92; PLAC1; placenta-specific 1; Placenta-specific protein 1
Gene Aliases: CT92; OOSP2L; PLAC1
UniProt ID: (Human) Q9HBJ0
Entrez Gene ID: (Human) 10761
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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