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This target displays homology in the following species: Cow: 93%; Dog: 86%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Zebrafish: 75%
The protein encoded by this gene is associated with the nuclear scaffold in proliferating cells. It was found to bind to the catalytic subunit of protein phosphatase-1 (PP1) and inhibit PP1 activity, suggesting that this protein may function as a regulatory subunit of PP1. Alternative splicing at this locus results in several transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Phosphatase and actin regulator 3; Scaffold-associated PP1-inhibiting protein; Scapinin
Gene Aliases: 1500003N10Rik; 4930415A02Rik; H17739; mKIAA4224; Phactr3; Scapin1; Scapinin
UniProt ID: (Mouse) Q8BYK5
Entrez Gene ID: (Mouse) 74189
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