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PA3-211 detects PEBP1 in human, mouse, and rat samples.
PA3-211 has successfully been used in Western blot, immunocytochemical, and immunohistochemical (paraffin) procedures.
The PA3-211 immunogen is a synthetic peptide corresponding to the C-terminal amino acids C(167)YQAEWDDYVPKLYEQLSGK(187) of PEBP1
PBP binds ATP, opioids and phosphatidylethanolamine, exhibiting a lower affinity for phosphatidylinositol and phosphatidylcholine. This serine protease inhibitor inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. PBP contains hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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