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Invitrogen
PARN Polyclonal Antibody
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FIGURE: 1 / 1
PARN Antibody (PA5-19552) in WB
Western blot analysis of Jurkat Whole Cell Lysate using Product # PA5-19552, PARN primary antibody at a dilution of 1 µg/mL (lane 1). Staining of A431 Whole Cell Lysate at a dilution of 1 µg/mL (lane 2). Blot treated with a secondary IR Dye680-conjugated Goat polyclonal anti-Rabbit antibody was used at a dilution of 1:10000.
Product Details
PA5-19552
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide conjugated to KLH derived from within residues 500 - 600 of Human PARN.
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_11006618
Product Specific Information
PA5-19552 targets PARN in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-19552 immunogen is synthetic peptide conjugated to KLH derived from within residues 500 - 600 of Human PARN.
PA5-19552 detects PARN which has a predicted molecular weight of approximately 75 kDa.
Target Information
The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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