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PAGE-3 (prostate-associated gene 3 protein), also known as GAGED1 (putative G antigen family Dmember 1), is a 113 amino acid protein that belongsto the GAGE family. The gene that encodes PAGE-3 consists of approximately 6,432 bases andmapsto human chromosome Xp11.21. Chromosome X consists of about 153million base pairs and nearly 1,000 genes. The combination of a X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number ofconditionsrelated to an unusual number and combination ofsexchromosomes being inherited, including Turner's syndrome, Klinefelter'ssyndrome and Triple X syndrome. Color blindness, hemophilia, and Duchennemuscular dystrophy arewellknown X chromosome-linked conditionswhich affectmalesmore frequently as males carry a single X chromosome.
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