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Invitrogen
P2Y12 (extracellular) Polyclonal Antibody
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FIGURE: 1 / 3
P2Y12 (extracellular) Antibody (PA5-111827) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of P2Y12 in human glioblastoma (U-87 MG) cells. A) Extracellular staining of cells using P2Y12 (extracellular) Antibody (Product # PA5-111827), (1:100) followed by goat anti-guinea pig-AlexaFluor-594 secondary antibody (red). DAPI was used as the counterstain (blue). B) Live view of the cells merged with P2Y12 staining.
Product Details
PA5-111827
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Guinea pig
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide corresponding to amino acid residues 270-282 of human P2RY12 (3rdextracellular loop)
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2857236
Product Specific Information
Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Peptide sequence is: CTAENTLFYV KES
Homology: Mouse - 12/13 amino acid residues identical; rat - 12/13 amino acid residues identical.
Target Information
P2Y12 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene. Expression of P2Y12 has been reported in platelets, spinal cord, and many brain regions. ESTs for P2Y12 have been isolated from B-cell/lung/testis, brain, embryo, prostate, eye, kidney carcinoma, and colon carcinoma libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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