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Invitrogen
OSCAR Monoclonal Antibody (5B8)
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Product Details
MA5-33374
Applications
Tested Dilution
Publications
Product Specifications
Published species
Mouse
Host/Isotype
Rat
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
5B8
Conjugate
Form
Liquid
Concentration
100 µg/mL
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2815512
Product Specific Information
Product is supplied at 1 mL (100 µL/mL).
Target Information
Recently, a novel member of the leukocyte receptor complex (LRC) encoded family has been identified that is expressed specifically in osteoclast (OC). This protein names OC-associated receptor or OSCAR, play critical roles in the regulation of both innate and adaptive immune responses and bone-specific regulator of OC differentiation. Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This protein family plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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