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Invitrogen
OPRK1 Polyclonal Antibody
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Product Details
PA1-4559
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues D(366) P A Y L R D I D G M N L P V(380) of the human KOR-1 protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Wet ice
RRID
AB_2156334
Product Specific Information
PA1-4559 detects kappa Opioid Receptor from human samples.
PA1-4559 has been successfully used in Western blotting applications. This antibody will detect a dominant band of ~46 kDa representing the monomer form of OPRK1, and may also detect dimmers or trimers as heterodimerization and homodimerization is common
The PA1-4559 immunogen is a synthetic peptide corresponding to residues D(366) P A Y L R D I D G M N L P V(380) of the human KOR-1 protein.
Target Information
This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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