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Working Concentration: 1.25 µg/mL. Sensitivity: 10 ng/mL Nalidixic Acid produces 37% inhibition in a competitive ELISA employing Nalidixic Acid polyclonal antibody.
Nalidixic Acid is a synthetic quinolone and antibacterial agent with urinary tract antiseptic activity. Nalidixic acid concentrates in the renal tubules and bladder and exerts its local antibacterial actions by interference of DNA gyrase activity, thereby inhibiting DNA synthesis during bacterial replication in a dose-dependent manner. Nalidixic acid is active against most gram-negative organisms that cause urinary tract infections. [National Center for Biotechnology Information. PubChem Compound Database; CID=4421].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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