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Invitrogen
NDST1 Polyclonal Antibody
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NDST1 Antibody (PA5-48535) in IHC (P)
Immunohistochemical analysis of NDST1 in formalin fixed and paraffin embedded human liver tissue. Samples were probed with a NDST1 Antibody (C-term) (Product # PA5-48535) followed by peroxidase conjugation of the secondary antibody and DAB staining.
Product Details
PA5-48535
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 820-849 amino acids from the C-terminal region of human NDST1.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2633992
Product Specific Information
Predicted to react with mouse and rat based on sequence homology.
Target Information
Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L- selectin ligands, thereby playing a role in inflammatory response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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