Invitrogen

NCS1 Polyclonal Antibody

Product Details

PA1-939

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic Peptide: D(161) G K L T L Q E F Q E G S K A D P S I V Q A L S L Y D G L V(190)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

AB_325938

Product Specific Information

PA1-939 detects neuronal calcium sensor-1 (NCS-1) from rat tissues.

PA1-939 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~20 kDa protein representing NCS-1 from rat brain extract.

PA1-939 immunizing peptide corresponds to amino acid residues 161-190 from rat NCS-1. This sequence is completely conserved in mouse, rat, chicken and human NCS-1. There is a single amino acid substitution in this region for Xenopus NCS-1.

Target Information

This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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