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Invitrogen
MMP7 Polyclonal Antibody
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Product Details
PA1-26608
Applications
Tested Dilution
Publications
Product Specifications
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MMP-7
Conjugate
Form
Liquid
Storage conditions
4°C, do not freeze
Shipping conditions
Wet ice
RRID
AB_794950
Product Specific Information
PA1-26608 detects MMP-7 from human samples.
PA1-26608 has been successfully used in immunohistochemistry (paraffin) procedures. This antibody detects a ~28 kDa band representing the pro form, and an ~18 kDa band representing the active form. No special pretreatment is required for immunostaining. Placenta tissues can be used as a positive control.
The PA1-26608 immunogen is MMP-7.
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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