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Invitrogen
LRRC8C Polyclonal Antibody
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Product Details
PA5-56118
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human LRRC8C
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2643556
Product Specific Information
Immunogen sequence: LERLSFSHNK IEVLPSHLFL CNKIRYLDLS YNDIRFIPPE IGVLQSLQYF SITCNKVESL PDELYFCKKL KTLKIGKNSL SVLSPKIGNL LFLSYLDVKG NHFEILPPEL GDCRALKRAG LVVEDALFET L
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
Target Information
LRRC8C is a protein coding gene. Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Plays a redundant role in the efflux of amino acids, such as aspartate and glutamate, in response to osmotic stress. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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