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Invitrogen
LPIN2 Polyclonal Antibody
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FIGURE: 1 / 1
LPIN2 Antibody (PA5-90683) in WB
Western blot analysis of LPIN2 in extracts of various cell lines. Samples were incubated with LPIN2 Polyclonal antibody (Product # PA5-90683) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s.
Product Details
PA5-90683
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 180-400 of human LPIN2 (NP_0554611)
Conjugate
Form
Liquid
Concentration
0.57 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806174
Product Specific Information
Immunogen sequence: TCDVGVSSDD DKGAQAARGS SNASLKEEEC KEPLLFHSGD HYPLSDGDWS PLETTYPQTA CPKSDSELEV KPAESLLRSE SHMEWTWGGF PESTKVSKRE RSDHHPRTAT ITPSENTHFR VIPSEDNLIS EVEKDASMED TVCTIVKPKP RALGTQMSDP TSVAELLEPP LESTQISSML DADHLPNAAL AEAPSESKPA AKVDSPSKKK GVHKRSQHQG P; Positive Samples: LO2, 293T, A-549, DU145, Mouse liver, Mouse lung, Mouse kidney, Mouse spleen; Cellular Location: Cytoplasm, Endoplasmic reticulum membrane, Nucleus, cytosol
Target Information
Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Lipin-2; Phosphatidate phosphatase LPIN2
Gene Aliases: 2610511G02Rik; AI481352; AW742896; KIAA0249; LPIN2
UniProt ID: (Human) Q92539, (Mouse) Q99PI5
Entrez Gene ID: (Human) 9663, (Mouse) 64898
transcription, DNA-templated
lipid metabolic process
phosphatidylethanolamine biosynthetic process
phosphatidylcholine biosynthetic process
fatty acid catabolic process
dephosphorylation
triglyceride biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
fatty acid metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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