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PA5-19804 targets LOX 1 in WB applications and shows reactivity with Human samples.
The PA5-19804 immunogen is synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human LOX 1.
PA5-19804 detects LOX 1 which has a predicted molecular weight of approximately 31 kDa.
LOX-1 (lectin-like oxidized LDL receptor -1) is a 40-50 kDa type II membrane glycoprotein class E scavenger receptor expressed by endothelial cells, macrophages, activated platelets and smooth muscle cells. LOX-1 binds to a wide range of ligands, including oxidized low-density lipoprotein (oxLDL), hypochlorite modified high-density lipoprotein (HDL), aged /apoptotic cells, activated platelets and bacteria, reflecting its versatile physiological functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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