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Invitrogen
LIS1 Polyclonal Antibody
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Product Details
PA1-26497
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a portion of human Lissencephaly 1 (Lis 1) protein encoded inpart by exons 3 and 4.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Storage conditions
4°C, do not freeze
Shipping conditions
Wet ice
Product Specific Information
PA1-26497 detects LIS1 from human samples. PA1-26497 is expected to cross react with mouse, rat, chicken, bovine, porcine, and Xenopus laevis due to sequence homology.
PA1-26497 has been successfully used in Western blot procedures.
The PA1-26497 immunogen is a synthetic peptide corresponding to a portion of human Lissencephaly 1 (Lis 1) protein encoded inpart by exons 3 and 4.
Target Information
VAMP7 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family, localizing to late endosomes and lysosomes. VAMP7 is thought to mediate the fusion of endosomes to their target lysosomes as well as other exocytosis events during phagocytosis and neuritogenesis. VAMP7 interacts with the VPS9 ankyrin repeat protein VARP, a protein that localizes to early endosomes and thought to regulate endosome dynamics. Together with CD82, VAMP7 can modulate the signaling of EGFR by regulating its endocytosis from the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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