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Invitrogen
LGR7 Polyclonal Antibody
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FIGURE: 1 / 1
LGR7 Antibody (PA1-41532) in WB
Western blot analysis of LGR7 in human heart lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse heart and 4) rat heart lysate using a Relaxin Receptor 1/LGR7 polyclonal antibody (Product # PA1-41532) at 0.5 ug/ml (human), 1 ug/ml (mouse) and 2 ug/ml (rat).
Product Details
PA1-41532
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues 50-100 of human Relaxin receptor 1.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2184714
Product Specific Information
PA1-41532 detects Relaxin receptor 1/LGR7 in monkey, chimpanzee, human, mouse and rat samples.
This antibody is expected to react with chicken, bovine, canine and opossum samples based on sequence homology.
Target Information
LGR7 is a low density lipoprotein receptor of 757amino acid belonging to the G-protein coupled receptor 1 family with rhodopsin-like receptor activity. It has seven transmembrane region, cysteine-rich motif, 10 LRR domains and 5 N-glycosylation sites in the N terminus. Research reports show that it has receptor for relaxins (RLN1 and RLN2) which stimulates adenylate cyclase activation, substrate adhesion, and chemo migratory capacity of mononuclear leukocytes. LGR7 is critical for mediating these biological responses by use of RNA interference lentiviral short hairpin constructs. It is widely expressed in 86% of 15 primary EC tissue samples including brain, kidney, testis and endometrium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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